Two things I'd really love to see are native controller support and something akin to the knapster mod as accessibility options.
I already use a controller layout someone on steam made, but it's somewhat wonky and having a better made one or native support would be a godsend.
As for the knapster option it should be just that: an option. Just a setting that individuals can choose themselves whether they want to use or not.
But NOT making the amount of voxels placed adjustable (for balance reasons obviously) really just automate the placing of voxels so it's easier for those with issues using a mouse for extended periods. It can be really painful on my wrists. :(